People will survive, and they will find happiness. Happiness only comes when you're not looking for it.

I admit I can't shake the idea that there is virtue in suffering, that there is a sort of psychic economy, whereby if you embrace success, happiness and comfort, these things have to be paid for.

I never was someone who was at ease with happiness.

Humility was considered a great virtue in my family household. No show of complacency or self-satisfaction was ever tolerated. Patting yourself on the back was definitely not encouraged, and pleasure or pride would be punishable by death.

I think my father gave me a great reverence for medical science. He was about as opposite to the personality of House as one could imagine. He was polite and easygoing, and would have gone to great lengths to make his patients feel attended to and heard and sympathized with.

Driving a motorcycle is like flying. All your senses are alive. When I ride through Beverly Hills in the early morning, and all the sprinklers have turned off, the scents that wash over me are just heavenly. Being House is like flying, too. You're free of the gravity of what people think.

I have my moments. Ever since I was a boy, I never was someone who was at ease with happiness. Too often I embrace introspection and self-doubt. I wish I could embrace the good things.

I don't have a single complete show or movie or anything else that I could look at and say, 'Nailed that one.' But endless dissatisfaction is, I suppose, what gets us out of bed in the morning.

Some people are drawn naturally - there are natural guitarists, and there are natural piano players, and I think guitar implies travel, a sort of footloose gypsy existence. You grab your bag and you go to the next town.

I don't have a single complete show or movie or anything else that I could look at and say, 'Nailed that one.' But endless dissatisfaction is, I suppose, what gets us out of bed in the morning.